Description

2-(4-Chlorophenyl)-5-Fluoro-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated indole structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, particularly for oncology and central nervous system (CNS) drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drugs.
• API Synthesis: Serves as a core structural unit in the synthesis of potential kinase inhibitors and receptor modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis Building Block: Utilized in academic and industrial laboratories for constructing complex heterocyclic compounds.

Basic Information

Product Name	2-(4-Chlorophenyl)-5-Fluoro-1H-Indole
CAS No.	881040-32-0
Molecular Formula	C14H9ClFN
Molecular Weight	245.68 g/mol
Synonyms	5-Fluoro-2-(4-chlorophenyl)-1H-indole; 2-(p-Chlorophenyl)-5-fluoroindole; 1H-Indole, 2-(4-chlorophenyl)-5-fluoro-; 881040-32-0; 2-(4-Chlorophenyl)-5-fluoroindole; 5-Fluoro-2-(4'-chlorophenyl)indole
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)-5-Fluoro-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.