Description

3-Bromo-1-(2-Ethoxy Naphthoyl)-7-Azaindole is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel small-molecule drugs, particularly kinase inhibitors and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Serves as a core scaffold or a functionalized fragment in the design and development of novel kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry & SAR Studies: Used extensively in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Biochemical Research: Employed as a tool compound in biochemical assays to study enzyme function and cellular signaling mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for pioneering research in organic synthesis and drug discovery methodologies.

Basic Information

Item	Details
Product Name	3-Bromo-1-(2-Ethoxy Naphthoyl)-7-Azaindole
CAS No.	880770-81-0
Molecular Formula	C19H15BrN2O2
Molecular Weight	383.24 g/mol
Synonyms	3-Bromo-1-(2-ethoxynaphthalene-1-carbonyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 3-bromo-1-[(2-ethoxynaphthoyl)]-; 3-Bromo-1-(2-ethoxy-1-naphthoyl)-7-azaindole; 7-Azaindole, 3-bromo-1-(2-ethoxynaphthoyl)-; 880770-81-0; BENA Intermediate; Kinase Inhibitor Intermediate AZD-1
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-1-(2-Ethoxy Naphthoyl)-7-Azaindole is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are characterized using advanced techniques including HPLC, NMR, and MS to meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.