Description

4-Bromo-1-Methyl-1H-Indole-2-Carboxylic Acid is a high-purity, synthetically valuable indole derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive bromine substituent and a carboxylic acid functional group, makes it an indispensable intermediate for constructing complex heterocyclic compounds. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders, inflammation, and oncology.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides by serving as a core scaffold for bioactive molecules.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and other transformations to introduce the indole moiety into more complex structures.
• Academic & R&D: Essential for methodological studies in organic chemistry and for exploring new synthetic pathways in university and corporate laboratories.

Basic Information

Product Name	4-Bromo-1-Methyl-1H-Indole-2-Carboxylic Acid
CAS No.	880349-08-6
Molecular Formula	C10H8BrNO2
Molecular Weight	254.08 g/mol
Synonyms	4-Bromo-1-methylindole-2-carboxylic acid; 1-Methyl-4-bromoindole-2-carboxylic acid; 2-Carboxy-4-bromo-1-methylindole; 880349-08-6; 4-Bromo-1-methyl-1H-indole-2-carboxylic acid; 4-Bromo-1-methylindole-2-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-1-Methyl-1H-Indole-2-Carboxylic Acid is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.