Description

4-Thien-2-Yltetrahydro-2H-Pyran-4-Carboxylic Acid 97% is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its unique heterocyclic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, polymers, and liquid crystals due to its fused thiophene and tetrahydropyran motifs.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and Institutional Research: Used in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	4-Thien-2-Yltetrahydro-2H-Pyran-4-Carboxylic Acid 97%
CAS No.	880166-18-7
Molecular Formula	C10H12O3S
Molecular Weight	212.27 g/mol
Synonyms	4-(Thiophen-2-yl)tetrahydro-2H-pyran-4-carboxylic acid; 4-(2-Thienyl)tetrahydro-2H-pyran-4-carboxylic Acid; 2H-Pyran-4-carboxylic acid, 4-(2-thienyl)tetrahydro-; 4-(Thien-2-yl)oxane-4-carboxylic acid; 880166-18-7; 4-Thien-2-yl-tetrahydropyran-4-carboxylic acid; 4-(2-Thienyl)-4-piperidinecarboxylic acid derivative (structural analog); THP-Thiophene-Carboxylic Acid (abbreviated)
EINECS	Contact for details

Quality Control

Our 4-Thien-2-Yltetrahydro-2H-Pyran-4-Carboxylic Acid 97% is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.