Description

Methyl 6-Fluoro-2-(4-(((Methoxycarbonyl)(Methyl)Amino)Methyl)Phenyl)-1H-Indole-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). Its precise molecular architecture makes it a critical building block for research and development in modern medicinal chemistry. This compound is primarily sought by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• API Synthesis: Serves as a crucial building block for constructing complex indole-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in research laboratories for structure-activity relationship (SAR) studies and lead optimization processes.
• Process Development & Scale-Up: Employed in the development and optimization of scalable, GMP-compliant manufacturing routes for target molecules.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method validation in API production.

Basic Information

Product Name	Methyl 6-Fluoro-2-(4-(((Methoxycarbonyl)(Methyl)Amino)Methyl)Phenyl)-1H-Indole-4-Carboxylate
CAS No.	880160-66-7
Molecular Formula	C21H21FN2O4
Molecular Weight	384.41 g/mol
Synonyms	6-Fluoro-2-[4-[[(methoxycarbonyl)(methyl)amino]methyl]phenyl]-1H-indole-4-carboxylic acid methyl ester; Methyl 6-fluoro-2-[4-[(N-methylmethoxycarbonylamino)methyl]phenyl]indole-4-carboxylate; 880160-66-7; 6-Fluoro-2-(4-((methoxycarbonyl(methyl)amino)methyl)phenyl)-1H-indole-4-carboxylic acid methyl ester; 4-Indolecarboxylic acid, 6-fluoro-2-[4-[[(methoxycarbonyl)(methyl)amino]methyl]phenyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-Fluoro-2-(4-(((Methoxycarbonyl)(Methyl)Amino)Methyl)Phenyl)-1H-Indole-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.