Description

3-Oxetanethiol is a specialized sulfur-containing heterocyclic building block featuring a reactive thiol group within a strained oxetane ring. This unique molecular architecture makes it a valuable intermediate for synthesizing novel compounds in advanced material science and pharmaceutical research. It is particularly sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and polymer industries for introducing sulfur functionalities and modifying physicochemical properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for the development of new active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting novel sulfur-containing heterocycles.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the oxetane-thiol moiety can enhance biological activity or environmental profile.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating polymers with specific properties like adhesion, refractive index modification, or chemical resistance.
• Ligand & Catalyst Development: Employed in the synthesis of novel ligands for metal catalysis, leveraging the thiol group for metal coordination.
• Chemical Biology Probes: Utilized in the design of probes and linkers for bioconjugation and protein modification studies due to its reactive thiol functionality.
• Fine Chemical Synthesis: A versatile building block for constructing complex organic molecules in custom synthesis and contract manufacturing projects.

Basic Information

Product Name	3-Oxetanethiol
CAS No.	880136-18-5
Molecular Formula	C3H6OS
Molecular Weight	90.14 g/mol
Synonyms	3-Mercaptooxetane; Oxetane-3-thiol; 3-Thiooxetanol; 3-Hydroxyoxetane thioether; Oxetan-3-yl mercaptan; 3-Oxetanylthiol; 880136-18-5 (CAS); 3-Oxetanthiol
EINECS	Contact for details

Quality Control

Every batch of 3-Oxetanethiol is produced and analyzed under strict quality management protocols to ensure consistency and reliability for your research and production needs. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates, ensuring traceability and compliance for global supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its sensitivity, keep away from strong oxidizing agents and minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.