Description

6-Bromo-2-Ethyl-3,4-Dihydroisoquinolin-1(2H)-One is a high-purity brominated isoquinolinone derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile halogenated scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its reactive bromine substituent and fused ring system.
• Chemical Synthesis: Serves as a precursor for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create diverse chemical libraries.
• Agrochemical Development: Employed in the research and synthesis of novel crop protection agents and pesticides.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	6-Bromo-2-Ethyl-3,4-Dihydroisoquinolin-1(2H)-One
CAS No.	879887-28-2
Molecular Formula	C₁₁H₁₂BrNO
Molecular Weight	254.12 g/mol
Synonyms	6-Bromo-2-ethyl-1,2,3,4-tetrahydroisoquinolin-1-one; 6-Bromo-2-ethyl-3,4-dihydro-1(2H)-isoquinolinone; 2-Ethyl-6-bromo-3,4-dihydroisoquinolin-1(2H)-one; 6-Bromo-2-ethyl-1,2,3,4-tetrahydroisoquinoline-1-one; 879887-28-2; 6-Bromo-2-ethyl-1-oxo-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-Ethyl-3,4-Dihydroisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.