Description

2-Benzylhexahydro-1H-Isoindol-4(2H)-One is a high-purity, advanced pharmaceutical intermediate with a complex bicyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in process development and scale-up for new drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, especially those targeting neurological pathways.
• Organic Synthesis Building Block: Used in research laboratories for constructing complex nitrogen-containing heterocycles due to its reactive ketone and protected amine functionalities.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale manufacturing of target molecules.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API production.
• Academic & Contract Research: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Product Name	2-Benzylhexahydro-1H-Isoindol-4(2H)-One
CAS No.	879687-90-8
Molecular Formula	C15H19NO
Molecular Weight	229.32 g/mol
Synonyms	2-Benzyloctahydroisoindol-4-one; 4(2H)-Isoindolone, 2-benzylhexahydro-1H-; 2-Benzyl-1,3,3a,4,7,7a-hexahydro-2H-isoindol-4-one; 2-Benzylhexahydroisoindol-4(2H)-one; Benzylhexahydroisoindolone
EINECS	Contact for details

Quality Control

Our 2-Benzylhexahydro-1H-Isoindol-4(2H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.