Description

4-(Aminomethyl)Tetrahydro-2H-Thiopyran-4-Ol is a versatile heterocyclic building block featuring both amino and hydroxyl functional groups on a saturated thiopyran ring. This unique bifunctional structure makes it a valuable intermediate for the synthesis of complex molecules in advanced research and development. It is particularly sought after by pharmaceutical and agrochemical R&D teams for creating novel active ingredients, such as enzyme inhibitors and receptor modulators. Its CAS number is 879514-92-8.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its sulfur-containing heterocycle.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics & Bioisosteres: The thiopyran ring can act as a bioisostere for phenyl or piperidine rings in medicinal chemistry programs.
• Polymer Modification: Functional monomer for introducing amino and hydroxyl groups into specialty polymers to alter solubility and reactivity.
• Chemical Biology Probes: Useful for synthesizing activity-based probes and molecular tags for studying biological processes.

Basic Information

Product Name	4-(Aminomethyl)Tetrahydro-2H-Thiopyran-4-Ol
CAS No.	879514-92-8
Molecular Formula	C7H15NOS
Molecular Weight	161.27 g/mol
Synonyms	4-(Aminomethyl)tetrahydro-2H-thiopyran-4-ol; 4-(Aminomethyl)thiacyclohexan-4-ol; 4-Hydroxy-4-(aminomethyl)thiane; 4-Aminomethyl-4-hydroxy-tetrahydro-thiopyran; 4-(Aminomethyl)-4-hydroxythiane; 4-Hydroxy-4-(aminomethyl)tetrahydro-2H-thiopyran; 4-(Aminomethyl)-4-hydroxytetrahydro-2H-thiopyran
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)Tetrahydro-2H-Thiopyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.