Description

tert-Butyl 2-Bromo-3-Cyclohexyl-1H-Indole-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated indole core and tert-butyl ester protecting group. This compound is of significant value for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, where precise molecular construction is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in lead optimization.
• API (Active Pharmaceutical Ingredient) Development: Used in the construction of the core indole structure for investigational new drugs.
• Chemical Biology Probes: Utilized in the creation of specialized molecular tools for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	tert-Butyl 2-Bromo-3-Cyclohexyl-1H-Indole-6-Carboxylate
CAS No.	879498-90-5
Molecular Formula	C19H24BrNO2
Molecular Weight	378.31 g/mol
Synonyms	2-Bromo-3-cyclohexyl-1H-indole-6-carboxylic acid tert-butyl ester; 1H-Indole-6-carboxylic acid, 2-bromo-3-cyclohexyl-, 1,1-dimethylethyl ester; tert-Butyl 2-bromo-3-cyclohexylindole-6-carboxylate; 2-Bromo-3-cyclohexylindole-6-carboxylic acid tert-butyl ester; 879498-90-5
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Bromo-3-Cyclohexyl-1H-Indole-6-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, for comprehensive identity confirmation and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each batch, documenting compliance with agreed specifications. Our quality commitment supports applications in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.