Description

3-(2-Hydroxy-4-Methylphenyl)-n-{4-[(3-Methyl-1-Piperidinyl)Sulfonyl]Phenyl}-1H-Pyrazole-5-Carboxamide is a sophisticated heterocyclic compound featuring a pyrazole core with a carboxamide linker and a substituted phenylsulfonyl piperidine moiety. This complex molecular architecture makes it a valuable high-purity intermediate for advanced research and development, particularly in the pharmaceutical sector. It is primarily sought after by R&D chemists and process development scientists working on novel therapeutic agents, especially within kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of targeted small-molecule drugs, particularly potential kinase inhibitors.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic and receptor binding assays to study biological pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of drug candidates.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs) under GMP-like conditions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and early-stage drug development services.

Basic Information

Product Name	3-(2-Hydroxy-4-Methylphenyl)-n-{4-[(3-Methyl-1-Piperidinyl)Sulfonyl]Phenyl}-1H-Pyrazole-5-Carboxamide
CAS No.	879463-03-3
Molecular Formula	C23H26N4O4S
Molecular Weight	454.55 g/mol
Synonyms	3-(2-Hydroxy-4-methylphenyl)-N-[4-[(3-methyl-1-piperidinyl)sulfonyl]phenyl]-1H-pyrazole-5-carboxamide; 1H-Pyrazole-5-carboxamide, 3-(2-hydroxy-4-methylphenyl)-N-[4-[(3-methyl-1-piperidinyl)sulfonyl]phenyl]-; UNII-8Z9Q2S8X7F; 8Z9Q2S8X7F; 879463-03-3; 3-(2-Hydroxy-4-methylphenyl)-N-(4-((3-methylpiperidin-1-yl)sulfonyl)phenyl)-1H-pyrazole-5-carboxamide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and reliability for critical R&D applications. Identity and purity are confirmed via advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical data is provided with each shipment to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.