Description

3-(2-Hydroxyphenyl)-n-(3-{[(2-Methoxyethyl)Amino]Carbonyl}-4,5,6,7-Tetrahydro-1-Benzothien-2-Yl)-1H-Pyrazole-5-Carboxamide is a sophisticated heterocyclic compound featuring a pyrazole core linked to a tetrahydrobenzothiophene scaffold, designed for advanced research and development. This molecule is of significant interest due to its potential as a key pharmacological intermediate or active pharmaceutical ingredient (API) precursor in drug discovery pipelines. It is primarily sought by pharmaceutical R&D teams, contract research organizations (CROs), and academic research institutions focused on medicinal chemistry and novel therapeutic agent synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties.
• Biochemical Probe Development: Acts as a tool compound for investigating specific biological pathways and target validation in early-stage discovery.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up synthesis under cGMP conditions for clinical trial material production.
• Academic Research: Utilized in university laboratories for pioneering studies in organic synthesis methodologies and heterocyclic chemistry.
• Reference Standard: Provides a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-(2-Hydroxyphenyl)-n-(3-{[(2-Methoxyethyl)Amino]Carbonyl}-4,5,6,7-Tetrahydro-1-Benzothien-2-Yl)-1H-Pyrazole-5-Carboxamide
CAS No.	879430-48-5
Molecular Formula	C22H24N4O4S
Molecular Weight	440.52 g/mol
Synonyms	3-(2-Hydroxyphenyl)-N-[3-[(2-methoxyethyl)carbamoyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl]-1H-pyrazole-5-carboxamide; 879430-48-5; UNII-8W8T171F8I; 1H-Pyrazole-5-carboxamide, 3-(2-hydroxyphenyl)-N-[3-[[(2-methoxyethyl)amino]carbonyl]-4,5,6,7-tetrahydro-1-benzothien-2-yl]-; 8W8T171F8I; CHEMBL3186472; BDBM50388895; AKOS009158269.
EINECS	Contact for details

Quality Control

Our 3-(2-Hydroxyphenyl)-n-(3-{[(2-Methoxyethyl)Amino]Carbonyl}-4,5,6,7-Tetrahydro-1-Benzothien-2-Yl)-1H-Pyrazole-5-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide full traceability and Certificates of Analysis (COA) detailing all specifications. Our quality commitment ensures the material is suitable for demanding R&D and pre-clinical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.