Description

1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrrolo[2,3-B]Pyridin-2(3H)-One is a sophisticated, high-purity organic intermediate featuring a protected pyrrolopyridinone core. This compound is critical for enabling complex synthetic routes in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Organic Synthesis Reagent: Used in advanced organic chemistry for constructing fused heterocyclic systems common in medicinal chemistry.
• Research & Development (R&D): Essential for academic and industrial research laboratories exploring new chemical entities and novel synthetic methodologies.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes during the development phase of new pharmaceuticals.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrrolo[2,3-B]Pyridin-2(3H)-One
CAS No.	879132-48-6
Molecular Formula	C14H22N2O2Si
Molecular Weight	278.43 g/mol
Synonyms	1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrrolo[2,3-b]pyridin-2(3H)-one; 1-((2-(Trimethylsilyl)ethoxy)methyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-2-one; 1H-Pyrrolo[2,3-b]pyridin-2(3H)-one, 1-((2-(trimethylsilyl)ethoxy)methyl)-; SEM-protected pyrrolopyridinone; 2-Oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-1-carbaldehyde, 2-(trimethylsilyl)ethyl acetal
EINECS	Contact for details

Quality Control

Our production of 1-((2-(Trimethylsilyl)Ethoxy)Methyl)-1H-Pyrrolo[2,3-B]Pyridin-2(3H)-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.