Description

n-Boc-4-Hydroxyindole is a protected indole derivative of significant importance in advanced organic synthesis. This high-purity building block is essential for the controlled introduction of the 4-hydroxyindole moiety into complex molecular architectures. It is primarily utilized by pharmaceutical and agrochemical research organizations for the development of novel active compounds, including kinase inhibitors and other biologically relevant molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of small molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes and activity-based protein profiling (ABPP) reagents.
• Material Science: Potential building block for advanced organic electronic materials and functional polymers.
• Academic & Contract Research: Employed in methodological development and the synthesis of complex natural product analogs.

Basic Information

Product Name	n-Boc-4-Hydroxyindole
CAS No.	879093-22-8
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.26 g/mol
Synonyms	1-Boc-4-hydroxyindole; tert-Butyl 4-hydroxy-1H-indole-1-carboxylate; 4-Hydroxyindole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-hydroxyindole; 4-Hydroxy-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; N-Boc-4-hydroxyindole; Boc-4-OH-indole
EINECS	Contact for details

Quality Control

Our n-Boc-4-Hydroxyindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.