Description

4-Fluoro-5-Methoxy-1-Methyl-1H-Indole is a high-purity, synthetically valuable fluorinated indole derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the introduction of a unique methoxy-fluoro substitution pattern. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging the biological activity of the fluorinated indole scaffold.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, functional group transformations, and the construction of complex heterocyclic systems.
• Material Science: Investigated as a monomer or functional component in the creation of specialty polymers and organic electronic materials.
• Chemical Biology Probe: Serves as a core structure for developing molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	4-Fluoro-5-Methoxy-1-Methyl-1H-Indole
CAS No.	879093-16-0
Molecular Formula	C10H10FNO
Molecular Weight	179.19 g/mol
Synonyms	1-Methyl-4-fluoro-5-methoxyindole; 4-Fluoro-5-methoxy-1-methylindole; 5-Methoxy-4-fluoro-1-methyl-1H-indole; 1H-Indole, 4-fluoro-5-methoxy-1-methyl-; 879093-16-0; 4-Fluoro-5-methoxy-1-methylindole; 1-Methyl-4-fluoro-5-methoxy-1H-indole
EINECS	Contact for details

Quality Control

Our 4-Fluoro-5-Methoxy-1-Methyl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.