Description

4-Hydroxy-Bicyclo[2.2.2]Octane-1-Carboxaldehyde is a high-purity, functionalized bicyclic aldehyde of significant interest in advanced organic synthesis. This compound matters as a versatile and structurally rigid building block, enabling the construction of complex molecular architectures with precise stereochemical control. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications ranging from medicinal chemistry to polymer precursors.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs) and complex natural product analogs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require a rigid, three-dimensional core structure.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the synthesis of specialty monomers for high-performance polymers, resins, and dendrimers.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including new cycloaddition and functionalization reactions.
• Flavor & Fragrance Chemistry: Potential use as an intermediate for synthesizing unique odorants and flavor compounds with complex olfactory profiles.

Basic Information

Product Name	4-Hydroxy-Bicyclo[2.2.2]Octane-1-Carboxaldehyde
CAS No.	878792-30-4
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	4-Hydroxybicyclo[2.2.2]octane-1-carbaldehyde; 1-Formyl-4-hydroxybicyclo[2.2.2]octane; 4-Hydroxy-BCO-CHO; Bicyclo[2.2.2]octane-1-carboxaldehyde, 4-hydroxy-; 4-Hydroxy-1-bicyclo[2.2.2]octanecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-Bicyclo[2.2.2]Octane-1-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.