Description

2-(Chloromethyl)-6-Methylthieno[2,3-D]Pyrimidin-4(3H)-One (Saltdata: Free) is a high-purity, advanced pharmaceutical intermediate characterized by its fused thienopyrimidine heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, valued for its role in synthesizing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly in oncology and antiviral therapeutic areas.
• Chemical Synthesis Building Block: Used in organic synthesis to construct complex heterocyclic scaffolds due to its reactive chloromethyl and carbonyl functional groups.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes for new molecular entities.
• Active Pharmaceutical Ingredient (API) Manufacturing: Serves as a crucial intermediate in the multi-step synthesis of final API compounds under current Good Manufacturing Practice (cGMP) standards.
• Contract Research & Development (CRO/CDMO): Supplied to service organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	2-(Chloromethyl)-6-Methylthieno[2,3-D]Pyrimidin-4(3H)-One (Saltdata: Free)
CAS No.	878699-59-3
Molecular Formula	C9H7ClN2OS
Molecular Weight	226.68 g/mol
Synonyms	2-(Chloromethyl)-6-methyl-3H-thieno[2,3-d]pyrimidin-4-one; 6-Methyl-2-(chloromethyl)thieno[2,3-d]pyrimidin-4(3H)-one; 4(3H)-Thieno[2,3-d]pyrimidinone, 2-(chloromethyl)-6-methyl-; Thieno[2,3-d]pyrimidine derivative (CAS 878699-59-3); 2-Chloromethyl-6-methylthieno[2,3-d]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-6-Methylthieno[2,3-D]Pyrimidin-4(3H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles as determined by advanced analytical techniques. We support development and commercial projects with material suitable for research use and can supply material manufactured under cGMP guidelines for advanced clinical and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.