Description

1-(2-Furylmethyl)-5-(Trifluoromethyl)-1H-Benzimidazol-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzimidazole core substituted with a furan and trifluoromethyl group. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and infectious diseases. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking a reliable and high-quality building block for complex synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzimidazole-based drug candidates targeting various disease pathways.
• Antiviral Agent Research: Used in the development of new antiviral compounds, leveraging the benzimidazole scaffold's known biological activity.
• Oncology Drug Discovery: Serves as a core structure for creating potential kinase inhibitors and other targeted cancer therapies.
• Agrochemical Development: Employed in research for new fungicides or herbicides, where the trifluoromethyl group enhances bioactivity and stability.
• Material Science Research: Investigated as a potential monomer or additive for creating specialized polymers with unique electronic or optical properties.
• Biochemical Tool Compound: Utilized in academic and industrial research as a probe to study specific enzyme interactions and biological mechanisms.

Basic Information

Product Name	1-(2-Furylmethyl)-5-(Trifluoromethyl)-1H-Benzimidazol-2-Amine
CAS No.	878465-57-7
Molecular Formula	C13H10F3N3O
Molecular Weight	281.24 g/mol
Synonyms	1-[(Furan-2-yl)methyl]-5-(trifluoromethyl)-1H-benzimidazol-2-amine; 2-Amino-1-(2-furanylmethyl)-5-(trifluoromethyl)benzimidazole; 5-(Trifluoromethyl)-1-(2-furylmethyl)-1H-benzimidazol-2-amine; 1H-Benzimidazol-2-amine, 1-(2-furanylmethyl)-5-(trifluoromethyl)-; Furan-2-ylmethyl substituted benzimidazole amine; FTBA Intermediate; CAS 878465-57-7
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Furylmethyl)-5-(Trifluoromethyl)-1H-Benzimidazol-2-Amine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.