Description

(S)-2-Methyl-n-(Thiophen-2-Ylmethylene)Propane-2-Sulfinamide is a high-purity chiral sulfinamide building block of significant importance in asymmetric synthesis. Its value lies in its role as a versatile chiral auxiliary and ligand, enabling the stereoselective construction of complex molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and fine chemicals requiring high enantiomeric purity.

Application

• As a chiral auxiliary in the asymmetric synthesis of amines and amino acid derivatives.
• As a ligand precursor for transition metal-catalyzed reactions, including additions and reductions.
• In the research and development of pharmaceutical intermediates for novel drug candidates.
• For the synthesis of agrochemical active ingredients requiring specific stereochemistry.
• In academic and industrial R&D for methodological studies in organic and medicinal chemistry.
• As a key starting material for the preparation of biologically active molecules with sulfur-containing heterocycles.

Basic Information

Product Name	(S)-2-Methyl-n-(Thiophen-2-Ylmethylene)Propane-2-Sulfinamide
CAS No.	878395-93-8
Molecular Formula	C9H13NOS2
Molecular Weight	215.33 g/mol
Synonyms	(S)-2-Methyl-N-(thiophen-2-ylmethylene)propane-2-sulfinamide; (S)-N-(Thiophen-2-ylmethylene)-2-methylpropane-2-sulfinamide; (S)-tert-Butanesulfinamide thiophene-2-carbaldehyde imine; (S)-2-Methyl-2-propanesulfinamide, N-[(2-thienyl)methylene]-; (S)-N-(2-Thienylmethylene)-2-methyl-2-propanesulfinamide; tert-Butanesulfinimine of 2-Thiophenecarboxaldehyde (S enantiomer); (S)-N-(Thiophene-2-carbonylidene)-tert-butanesulfinamide
EINECS	Contact for details

Quality Control

Our (S)-2-Methyl-n-(Thiophen-2-Ylmethylene)Propane-2-Sulfinamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.