Description

tert-Butyl 5-(Aminomethyl)Thiazol-2-Ylcarbamate is a high-value, protected intermediate featuring a reactive aminomethyl group on a thiazole core. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Peptidomimetic Chemistry: Used to incorporate thiazole-based scaffolds into peptide analogs to enhance metabolic stability and binding affinity.
• Chemical Biology Probes: Serves as a precursor for developing labeled compounds or affinity probes for target identification and validation studies.
• Agrochemical Research: Intermediate in the development of new fungicides or herbicides that utilize heterocyclic chemistry.
• Material Science: Potential monomer or cross-linker for creating specialized polymers with unique electronic or optical properties.

Basic Information

Product Name	tert-Butyl 5-(Aminomethyl)Thiazol-2-Ylcarbamate
CAS No.	878376-13-7
Molecular Formula	C9H15N3O2S
Molecular Weight	229.30 g/mol
Synonyms	2-Thiazolecarbamic acid, 5-(aminomethyl)-, 1,1-dimethylethyl ester; tert-Butyl N-(5-aminomethylthiazol-2-yl)carbamate; 5-(Aminomethyl)-2-thiazolecarbamic acid 1,1-dimethylethyl ester; 2-((tert-Butoxycarbonyl)amino)-5-(aminomethyl)thiazole; BOC-5-Aminomethylthiazole-2-carbamate; N-Boc-5-aminomethyl-2-aminothiazole
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-(Aminomethyl)Thiazol-2-Ylcarbamate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere when possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.