Description

2-(Piperidin-1-Ylmethyl)Phenylboronic Acid is a specialized boronic acid derivative that serves as a crucial building block in modern synthetic chemistry. Its molecular structure, featuring a phenylboronic acid moiety linked to a piperidine ring via a methylene spacer, makes it a valuable reagent for cross-coupling reactions and medicinal chemistry research. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and metabolic disorders.
• Suzuki-Miyaura Cross-Coupling: Acts as a versatile boronic acid partner for palladium-catalyzed carbon-carbon bond formation, essential for constructing biaryl and heterobiaryl structures.
• Medicinal Chemistry & SAR Studies: Used to introduce the 2-(piperidin-1-ylmethyl)phenyl fragment into molecular scaffolds to explore structure-activity relationships and optimize pharmacokinetic properties.
• Ligand Synthesis: Serves as a starting material for the preparation of novel ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying enzyme function and biological pathways.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	2-(Piperidin-1-Ylmethyl)Phenylboronic Acid
CAS No.	878289-33-9
Molecular Formula	C13H20BNO2
Molecular Weight	233.12 g/mol
Synonyms	[2-(Piperidin-1-ylmethyl)phenyl]boronic acid; 2-(Piperidin-1-ylmethyl)benzeneboronic acid; 2-[(Piperidin-1-yl)methyl]phenylboronic Acid; 1-Piperidinemethanol, α-(2-boronophenyl)-; B-[2-(1-Piperidinylmethyl)phenyl]boronic acid; 878289-33-9; 2-Piperidin-1-ylmethyl-phenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-(Piperidin-1-Ylmethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting your quality assurance and regulatory compliance needs in research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.