Description

1H-Benzimidazole-6-Carbonitrile, 2-(Aminomethyl)- is a high-purity, functionalized benzimidazole derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical pharmaceutical intermediate, enabling the construction of complex molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and receptor antagonist research.
• Agrochemical Synthesis: Used in the development of new fungicides and herbicides, leveraging the bioactive benzimidazole core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors and advanced polymers due to its electron-deficient nitrile group and aromatic structure.
• Bioconjugation and Probe Synthesis: The aminomethyl group provides a handle for conjugation, useful in creating fluorescent probes or bioconjugates for diagnostic applications.

Basic Information

Product Name	1H-Benzimidazole-6-Carbonitrile, 2-(Aminomethyl)-
CAS No.	878025-51-5
Molecular Formula	C9H8N4
Molecular Weight	172.19 g/mol
Synonyms	2-(Aminomethyl)-1H-benzimidazole-6-carbonitrile; 6-Cyano-2-aminomethylbenzimidazole; 2-(Aminomethyl)-6-cyano-1H-benzimidazole; 1H-Benzimidazole-6-carbonitrile, 2-(aminomethyl)-; 2-(Aminomethyl)-1H-1,3-benzodiazole-6-carbonitrile; Benzimidazole-6-carbonitrile, 2-(aminomethyl)-; 878025-51-5; 2-Aminomethyl-6-cyanobenzimidazole
EINECS	Contact for details

Quality Control

Our 1H-Benzimidazole-6-Carbonitrile, 2-(Aminomethyl)- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.