Description

5-Cyano-1H-Indole-2-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its indole-based heterocyclic structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of targeted therapies, particularly in oncology and neurological research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted small molecules.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Used in the construction of more complex indole-containing heterocycles for various chemical and material science applications.
• Biochemical Research: Potential use as a probe or inhibitor in enzymatic studies due to its specific molecular recognition properties.

Basic Information

Product Name	5-Cyano-1H-Indole-2-Carboxamide
CAS No.	877998-55-5
Molecular Formula	C10H7N3O
Molecular Weight	185.18 g/mol
Synonyms	5-Cyanoindole-2-carboxamide; 1H-Indole-2-carboxamide, 5-cyano-; 2-Carbamoyl-5-cyanoindole; 5-Cyano-1H-indole-2-carboxylic acid amide; 877998-55-5; 5-CN-indole-2-CONH2
EINECS	Contact for details

Quality Control

Our 5-Cyano-1H-Indole-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR, MS). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.