Description

2-(Chloromethyl)-6,7,8,9-Tetrahydro-5H-Cyclohepta[4,5]Thieno[2,3-D]Pyrimidin-4-Amine is a high-value, heterocyclic organic building block featuring a fused thienopyrimidine core. This compound is critical for advanced pharmaceutical research and development, serving as a versatile intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic scaffold.
• Chemical Biology Probe Development: Serves as a core structure for creating tool compounds to study biological pathways and target validation.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials and advanced polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects.

Basic Information

Product Name	2-(Chloromethyl)-6,7,8,9-Tetrahydro-5H-Cyclohepta[4,5]Thieno[2,3-D]Pyrimidin-4-Amine
CAS No.	877964-68-6
Molecular Formula	C₁₂H₁₄ClN₃S
Molecular Weight	267.78 g/mol
Synonyms	2-(Chloromethyl)-4-amino-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidine; 4-Amino-2-(chloromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[4,5]thieno[2,3-d]pyrimidine; 877964-68-6; Thieno[2,3-d]pyrimidine, 2-(chloromethyl)-6,7,8,9-tetrahydro-4-amino-5H-cyclohepta[4,5]-; Cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-amine, 2-(chloromethyl)-6,7,8,9-tetrahydro-5H-
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-6,7,8,9-Tetrahydro-5H-Cyclohepta[4,5]Thieno[2,3-D]Pyrimidin-4-Amine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.