Description

3,4-Dihydro-6-Iodo-1(2H)-Isoquinolinone is a high-purity iodinated isoquinolinone derivative, serving as a critical pharmaceutical intermediate and research chemical. Its unique halogenated structure makes it a valuable building block for medicinal chemistry, particularly in the development of novel bioactive compounds. This product is essential for researchers and manufacturers in pharmaceutical R&D and fine chemical synthesis who require reliable, high-quality intermediates for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and other transformations to introduce the iodinated isoquinolinone moiety.
• Chemical Reference Standard: Serves as an analytical standard for quality control and method development in laboratories.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and reaction mechanisms.
• Agrochemical Intermediate: Potential use in the synthesis of novel active ingredients for crop protection.

Basic Information

Item	Details
Product Name	3,4-Dihydro-6-Iodo-1(2H)-Isoquinolinone
CAS No.	877868-87-6
Molecular Formula	C9H8INO
Molecular Weight	273.07 g/mol
Synonyms	6-Iodo-3,4-dihydro-1(2H)-isoquinolinone; 6-Iodo-1,2,3,4-tetrahydroisoquinolin-1-one; 6-Iodoisoquinolin-1(2H)-one, 3,4-dihydro-; 877868-87-6; 3,4-Dihydro-6-iodo-2H-isoquinolin-1-one; 6-Iodo-3,4-dihydroisoquinolin-1(2H)-one
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-6-Iodo-1(2H)-Isoquinolinone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistent identity. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.