Description

1H-Imidazo[1,2-A]Imidazole,2,3,5,6-Tetrahydro-2,6-Bis(Phenylmethyl)-, (2S,6S)- is a high-purity, stereochemically defined chiral intermediate of significant importance in modern pharmaceutical synthesis. Its value lies in its complex, fused bicyclic imidazole structure, which serves as a privileged scaffold for developing novel active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly in areas requiring sophisticated chiral building blocks.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the development of new asymmetric synthetic methodologies.
• Medicinal Chemistry: Provides the core imidazo-imidazole scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for potential APIs during late-stage development.
• Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying biological pathways and protein function.

Basic Information

Product Name	1H-Imidazo[1,2-A]Imidazole,2,3,5,6-Tetrahydro-2,6-Bis(Phenylmethyl)-, (2S,6S)-
CAS No.	877773-30-3
Molecular Formula	C20H22N4
Molecular Weight	318.42 g/mol
Synonyms	(2S,6S)-2,6-Dibenzyl-2,3,5,6-tetrahydro-1H-imidazo[1,2-a]imidazole; (2S,6S)-2,6-Dibenzyl-1,4,5,6-tetrahydroimidazo[1,2-a]imidazole; (2S,6S)-2,6-Bis(phenylmethyl)-2,3,5,6-tetrahydro-1H-imidazo[1,2-a]imidazole; (2S,6S)-2,6-Dibenzyl-2,3,5,6-tetrahydroimidazo[1,2-a]imidazole; 1H-Imidazo[1,2-a]imidazole, 2,3,5,6-tetrahydro-2,6-bis(phenylmethyl)-, (2S,6S)-; Chiral Imidazo-imidazole Derivative; CAS 877773-30-3
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. For this advanced intermediate, quality is assured through stringent analytical controls including chiral HPLC to confirm stereochemical purity and NMR for structural verification, meeting the exacting requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.