Description

4-(5-Aminosulfonylthiophen-2-Yl)Benzoic Acid is a high-purity, specialized organic compound featuring a benzoic acid core linked to an aminosulfonyl-substituted thiophene moiety. This unique bifunctional structure makes it a valuable pharmaceutical intermediate and research chemical for the synthesis of novel active molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate its distinct sulfonamide and carboxylic acid functionalities into target compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting enzymes where the sulfonamide group acts as a pharmacophore.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or plant growth regulators that leverage its specific chemical reactivity.
• Organic Synthesis Reagent: Serves as a versatile precursor in organic chemistry for constructing complex heterocyclic systems and functionalized aromatic compounds.
• Material Science: Potential monomer or additive for creating specialized polymers with tailored electronic or thermal properties.
• Bioconjugation & Probe Development: The carboxylic acid group allows for coupling to biomolecules, making it useful for creating chemical probes or diagnostic agents.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Item	Detail
Product Name	4-(5-Aminosulfonylthiophen-2-Yl)Benzoic Acid
CAS No.	877758-90-2
Molecular Formula	C11H9NO4S2
Molecular Weight	283.32 g/mol
Synonyms	4-(5-Sulfamoylthiophen-2-yl)benzoic acid; 2-Thiophenesulfonamide, 5-(4-carboxyphenyl)-; 5-(4-Carboxyphenyl)thiophene-2-sulfonamide; Benzoic acid, 4-(5-sulfamoyl-2-thienyl)-; [877758-90-2]
EINECS	Contact for details

Quality Control

Every batch of 4-(5-Aminosulfonylthiophen-2-Yl)Benzoic Acid is produced and tested under a strict quality management system. We guarantee high purity and batch-to-batch consistency through comprehensive analytical protocols including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to ensure it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.