Description

2-Bromo-5-(Pyrrolidine-1-Carbonyl)-1,3-Thiazole is a high-value, heterocyclic building block featuring a bromothiazole core functionalized with a pyrrolidine amide moiety. This compound matters for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole ring.
• Material Science Research: Acts as a precursor for functionalized heterocycles used in the development of organic semiconductors, ligands, or advanced polymers.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.
• Academic Research: Employed in university and institutional laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	2-Bromo-5-(Pyrrolidine-1-Carbonyl)-1,3-Thiazole
CAS No.	877675-06-4
Molecular Formula	C8H9BrN2OS
Molecular Weight	261.14 g/mol
Synonyms	2-Bromo-5-(1-pyrrolidinecarbonyl)thiazole; 1-(2-Bromo-1,3-thiazol-5-yl)-1-pyrrolidinylmethanone; 2-Bromo-5-(pyrrolidine-1-carbonyl)thiazole; 2-Bromo-5-pyrrolidin-1-ylcarbonyl-1,3-thiazole; 877675-06-4; Thiazole, 2-bromo-5-(1-pyrrolidinylcarbonyl)-; 2-Bromo-5-(N-pyrrolidinylcarbonyl)thiazole
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Pyrrolidine-1-Carbonyl)-1,3-Thiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to quality supports your research and development needs with reliable, high-purity materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.