Description

5-Thiazolecarboxaldehyde, 2-(Methoxymethyl)- is a specialized heterocyclic aldehyde building block of significant interest in advanced organic synthesis. Its core value lies in its dual functional groups—the reactive aldehyde and the thiazole ring—which make it a versatile precursor for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, antiviral agents, and anti-inflammatory compounds.
• Agrochemical Synthesis: Serves as a crucial building block in the research and production of next-generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the synthesis of specialized ligands for metal catalysis and organocatalysts, enabling novel synthetic transformations.
• Material Science Precursor: Employed in the research of organic electronic materials, such as components for OLEDs or conductive polymers, due to the electron-rich thiazole moiety.
• Chemical Biology Probe Synthesis: Utilized to create tagged molecules or activity-based probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global R&D projects.

Basic Information

Product Name	5-Thiazolecarboxaldehyde, 2-(Methoxymethyl)-
CAS No.	877398-86-2
Molecular Formula	C6H7NO2S
Molecular Weight	157.19 g/mol
Synonyms	2-(Methoxymethyl)thiazole-5-carboxaldehyde; 2-(Methoxymethyl)-1,3-thiazole-5-carbaldehyde; 5-Formyl-2-(methoxymethyl)thiazole; 2-Methoxymethyl-5-thiazolecarboxaldehyde; Thiazole-5-carboxaldehyde, 2-(methoxymethyl)-; 877398-86-2; 2-Methoxymethylthiazole-5-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-Thiazolecarboxaldehyde, 2-(Methoxymethyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. For projects requiring specific regulatory support, we can discuss compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is easily oxidized; ensure containers are properly sealed after each use to minimize exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.