Description

1H-Indazole-1-Carboxylicacid,5-(2-Bromoacetyl)-,1,1-Dimethylethylester CAS NO 877264-74-9 is a high-purity, specialized organic intermediate featuring a reactive bromoacetyl group and a protected carboxylic acid function. This compound is a critical building block for the synthesis of complex heterocyclic molecules, offering precise control over molecular architecture in advanced chemical processes. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, particularly for creating novel indazole-based active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel indazole-based drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its versatile reactive sites for further functionalization.
• Agrochemical Synthesis: Serves as a building block for developing new crop protection agents and herbicides with specific biological activity.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology: Used in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific, multi-step synthetic routes.

Basic Information

Product Name	1H-Indazole-1-Carboxylicacid,5-(2-Bromoacetyl)-,1,1-Dimethylethylester
CAS No.	877264-74-9
Molecular Formula	C14H15BrN2O3
Molecular Weight	339.19 g/mol
Synonyms	tert-Butyl 5-(2-bromoacetyl)-1H-indazole-1-carboxylate; 1-(tert-Butoxycarbonyl)-5-(2-bromoacetyl)indazole; 5-(2-Bromoacetyl)-1H-indazole-1-carboxylic acid 1,1-dimethylethyl ester; 5-(Bromoacetyl)-1-(tert-butoxycarbonyl)-1H-indazole; 1-Boc-5-(2-bromoacetyl)indazole; Boc-5-(bromoacetyl)indazole; 877264-74-9
EINECS	Contact for details

Quality Control

Our 1H-Indazole-1-Carboxylicacid,5-(2-Bromoacetyl)-,1,1-Dimethylethylester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.