Description

1H-Indazole-1-Carboxylic Acid, 5-Acetyl-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate with the CAS number 877264-73-8. This compound is a critical building block in modern organic synthesis, valued for its role in constructing complex heterocyclic scaffolds. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Used in research and development for constructing complex indazole-based heterocyclic compounds.
• Agrochemical Research: Serves as a starting material for developing new crop protection agents and herbicides.
• Material Science: Potential application in the synthesis of specialty polymers and advanced organic materials.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for methodological studies and discovery chemistry.

Basic Information

Product Name	1H-Indazole-1-Carboxylic Acid, 5-Acetyl-, 1,1-Dimethylethyl Ester
CAS No.	877264-73-8
Molecular Formula	C₁₆H₂₀N₂O₃
Molecular Weight	288.34 g/mol
Synonyms	5-Acetyl-1H-indazole-1-carboxylic acid tert-butyl ester; tert-Butyl 5-acetyl-1H-indazole-1-carboxylate; 5-Acetyl-1-(tert-butoxycarbonyl)-1H-indazole; 1-(tert-Butoxycarbonyl)-5-acetylindazole; 877264-73-8; 5-Acetyl-1-Boc-indazole; Boc-5-acetylindazole
EINECS	Contact for details

Quality Control

Our 1H-Indazole-1-Carboxylic Acid, 5-Acetyl-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.