Description

Benzo[B]Thiophen-6-Yl Trifluoromethanesulfonate is a high-value triflate ester derivative, serving as a versatile and reactive synthetic intermediate in advanced organic chemistry. Its primary commercial value lies in enabling efficient cross-coupling reactions, particularly in the construction of complex heterocyclic and pharmaceutical scaffolds. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce the benzo[b]thiophene moiety into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing the benzo[b]thiophene core found in various therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific heterocyclic architectures.
• Material Science Research: Employed in the creation of organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs), where its structure can influence charge transport properties.
• Cross-Coupling Reactions: Acts as an excellent electrophile in palladium-catalyzed reactions like Suzuki, Negishi, and Stille couplings to form carbon-carbon bonds.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	Benzo[B]Thiophen-6-Yl Trifluoromethanesulfonate
CAS No.	877264-48-7
Molecular Formula	C9H5F3O3S2
Molecular Weight	282.26 g/mol
Synonyms	6-(Trifluoromethanesulfonyloxy)benzo[b]thiophene; 6-Benzo[b]thienyl Triflate; Benzo[b]thiophen-6-yl Triflate; 6-Trifluoromethanesulfonyloxy-1-benzothiophene; 1-Benzothiophen-6-yl trifluoromethanesulfonate; Trifluoromethanesulfonic Acid Benzo[b]thiophen-6-yl Ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity chemical intermediates. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.