Description

3-Cyano-4-Pyrrolidinophenylboronic Acid is a specialized boronic acid derivative that serves as a crucial building block in modern synthetic chemistry. Its molecular structure, featuring both a boronic acid group and a cyano-substituted pyrrolidine ring, makes it a highly valuable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and protease inhibitor research.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, essential for constructing biaryl structures.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and combinatorial chemistry libraries to explore new chemical entities and their biological activities.
• Chemical Biology Probes: Employed in the development of molecular probes and sensors for studying biological processes and enzyme functions.
• Advanced Material Synthesis: Serves as a monomer or functionalizing agent in the creation of organic electronic materials and polymers with specific optoelectronic properties.
• Agrochemical Research: Utilized in the discovery and development of new crop protection agents and herbicides.

Basic Information

Product Name	3-Cyano-4-Pyrrolidinophenylboronic Acid
CAS No.	876918-90-0
Molecular Formula	C11H13BN2O2
Molecular Weight	216.05 g/mol
Synonyms	4-(Pyrrolidin-1-yl)-3-cyanophenylboronic Acid; (3-Cyano-4-pyrrolidin-1-ylphenyl)boronic Acid; 3-Cyano-4-(1-pyrrolidinyl)benzeneboronic Acid; B-[3-Cyano-4-(pyrrolidin-1-yl)phenyl]boronic Acid; 876918-90-0; 3-CN-4-Pyrrolidinophenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 3-Cyano-4-Pyrrolidinophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.