Description

2-[3-(3,4-Dihydro-6,7-Dimethoxy-2(1H)-Isoquinolinyl)Propyl]-1H-Isoindole-1,3(2H)-Dione is a specialized heterocyclic organic compound featuring a phthalimide moiety linked to a tetrahydroisoquinoline core. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules, particularly those targeting neurological pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Alkaloid Analog Synthesis: Employed in the preparation of synthetic analogs of tetrahydroisoquinoline alkaloids for biological evaluation.
• Biochemical Tool Compound: Potential use in developing probes for studying enzyme inhibition or receptor binding assays.
• Fine Chemical Production: Integrated into multi-step synthetic routes for high-value, low-volume specialty chemicals.

Basic Information

Product Name	2-[3-(3,4-Dihydro-6,7-Dimethoxy-2(1H)-Isoquinolinyl)Propyl]-1H-Isoindole-1,3(2H)-Dione
CAS No.	876751-49-4
Molecular Formula	C22H24N2O4
Molecular Weight	380.44 g/mol
Synonyms	N-[3-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)propyl]phthalimide; 2-[3-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)propyl]isoindoline-1,3-dione; 1H-Isoindole-1,3(2H)-dione, 2-[3-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)propyl]-; Phthalimide, N-[3-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)propyl]-; Tetrahydroisoquinoline-phthalimide conjugate
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.