Description

5-Amino-4-Cyano-3-[[(4-Fluorophenyl)Thio]Methyl]-2-Thiophenecarboxylic Acid Ethyl Ester is a high-purity, multi-functional heterocyclic building block designed for advanced organic synthesis. This compound is critical for research and development in pharmaceutical chemistry, offering a versatile scaffold for constructing complex molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its thiophene and fluorinated arylthioether motifs for bioactivity.
• Material Science: Acts as a monomer or functional additive in the research of specialty polymers and organic electronic materials due to its conjugated thiophene core.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and the development of chemical tools for biological target identification.
• Custom Synthesis: A valuable starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis and library production for drug discovery programs.

Basic Information

Product Name	5-Amino-4-Cyano-3-[[(4-Fluorophenyl)Thio]Methyl]-2-Thiophenecarboxylic Acid Ethyl Ester
CAS No.	876678-06-7
Molecular Formula	C16H15FN2O2S2
Molecular Weight	350.43 g/mol
Synonyms	Ethyl 5-Amino-4-cyano-3-[(4-fluorophenylthio)methyl]thiophene-2-carboxylate; 5-Amino-4-cyano-3-((4-fluorophenylthio)methyl)thiophene-2-carboxylic acid ethyl ester; 876678-06-7; 3-[(4-Fluorophenylsulfanyl)methyl]-5-amino-4-cyanothiophene-2-carboxylic acid ethyl ester; 5-Amino-4-cyano-3-[[(4-fluorophenyl)thio]methyl]-2-thiophenecarboxylic acid, ethyl ester
EINECS	Contact for details

Quality Control

Our production of 5-Amino-4-Cyano-3-[[(4-Fluorophenyl)Thio]Methyl]-2-Thiophenecarboxylic Acid Ethyl Ester adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.