Description

Piperidine-3-Thiol CAS NO 876507-88-9 is a specialized heterocyclic building block featuring a piperidine scaffold with a thiol functional group. This compound is valued for its dual functionality, serving as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and metabolic disorder research.
• Ligand Synthesis: Used in the preparation of chelating agents and catalysts for asymmetric synthesis and metal complexation.
• Peptidomimetics: Incorporated into peptide analogs to enhance stability, bioavailability, or to introduce specific conformational constraints.
• Agrochemical Development: Serves as a precursor in the creation of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Utilized in the development of polymers, resins, and functional surfaces where the thiol group enables cross-linking or surface modification.
• Chemical Biology Probes: Acts as a scaffold for creating probes to study enzyme function or protein-protein interactions.

Basic Information

Product Name	Piperidine-3-Thiol
CAS No.	876507-88-9
Molecular Formula	C5H11NS
Molecular Weight	117.21 g/mol
Synonyms	3-Mercaptopiperidine; 3-Piperidinethiol; Piperidine-3-thiol; 3-Thiolpiperidine; 1,2,3,4,5,6-Hexahydro-3-pyridinethiol; 3-Piperidinol, thio-; 3-Sulfanylpiperidine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Piperidine-3-Thiol is analyzed to confirm identity, purity, and consistency. We adhere to strict in-process controls and final release specifications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request. Our quality system is designed to support cGMP manufacturing for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Due to its highly volatile and easily oxidized nature, containers must be kept tightly sealed and away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.