Description

5-Trifluoromethoxybenzothiazole is a high-value, fluorinated heterocyclic building block essential for advanced chemical synthesis. Its unique structure, featuring both a benzothiazole core and a trifluoromethoxy substituent, makes it a critical intermediate for developing novel compounds with enhanced properties. This product is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries to create new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve metabolic stability and bioavailability.
• Material Science Precursor: Serves as a building block for advanced polymers, liquid crystals, and organic electronic materials due to its electron-deficient aromatic system.
• Fluorinated Compound Library Synthesis: Essential for constructing diverse screening libraries in drug discovery, enabling the exploration of structure-activity relationships (SAR).
• Chemical Biology Probe Development: Utilized to create tagged or labeled molecules for studying biological pathways and target engagement.

Basic Information

Item	Details
Product Name	5-Trifluoromethoxybenzothiazole
CAS No.	876500-74-2
Molecular Formula	C8H4F3NOS
Molecular Weight	219.18 g/mol
Synonyms	5-(Trifluoromethoxy)-1,3-benzothiazole; 5-(Trifluoromethoxy)benzothiazole; Benzothiazole, 5-(trifluoromethoxy)-; 2-(Trifluoromethoxy)benzothiazole (isomer); 5-Trifluoromethoxy benzothiazole; 5-Trifluoromethoxy-benzo[d]thiazole; 5-(Trifluoromethoxy)benzo[d]thiazole; 5-Trifluoromethoxy-1,3-benzothiazole
EINECS	Contact for details

Quality Control

Our 5-Trifluoromethoxybenzothiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.