Description

5-(Bromomethyl)-2,4-Diphenyl-1,3-Thiazole is a high-value, functionalized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the reactive bromomethyl group, which serves as a versatile handle for further chemical elaboration, enabling the construction of complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting various disease pathways where the thiazole core is pharmacologically active.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organocatalysis.
• Functional Material Precursor: Employed in the synthesis of organic semiconductors, liquid crystals, or fluorescent dyes due to the conjugated diphenylthiazole system.
• Chemical Biology Probe: Useful for tagging or modifying biomolecules in research applications, exploiting the reactivity of the bromomethyl group.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.

Basic Information

Product Name	5-(Bromomethyl)-2,4-Diphenyl-1,3-Thiazole
CAS No.	876316-44-8
Molecular Formula	C16H12BrNS
Molecular Weight	330.24 g/mol
Synonyms	5-(Bromomethyl)-2,4-diphenylthiazole; 2,4-Diphenyl-5-(bromomethyl)thiazole; 5-Bromomethyl-2,4-diphenylthiazole; Thiazole, 5-(bromomethyl)-2,4-diphenyl-; 876316-44-8; 5-Bromomethyl-2,4-diphenyl-1,3-thiazole
EINECS	Contact for details

Quality Control

Our 5-(Bromomethyl)-2,4-Diphenyl-1,3-Thiazole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee consistency and support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.