Description

1H-Indole-1-Carboxylic Acid, 2-Borono-6-(Trifluoromethyl)-, 1-(1,1-Dimethylethyl) Ester (9Ci) is a specialized organoboron building block of significant interest in advanced synthetic chemistry. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel indole-based scaffolds. The CAS number for this compound is 875558-27-3.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds in complex molecule assembly.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the indole and trifluoromethyl motifs.
• Material Science & OLED Development: Acts as a precursor for creating advanced organic electronic materials and emissive layers in display technologies.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 2-Borono-6-(Trifluoromethyl)-, 1-(1,1-Dimethylethyl) Ester (9Ci)
CAS No.	875558-27-3
Molecular Formula	C₁₄H₁₅BF₃NO₄
Molecular Weight	329.08 g/mol
Synonyms	tert-Butyl 2-borono-6-(trifluoromethyl)-1H-indole-1-carboxylate; 2-Borono-6-(trifluoromethyl)-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 875558-27-3; 1-(tert-Butoxycarbonyl)-2-borono-6-(trifluoromethyl)indole; BOC-2-Borono-6-CF3-Indole; 2-Boron-6-(trifluoromethyl)-1H-indole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid, 2-Borono-6-(Trifluoromethyl)-, 1-(1,1-Dimethylethyl) Ester (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term preservation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.