Description

(Ethyl-D5)Triphenylphosphonium Bromide is a deuterated organophosphorus reagent, specifically a Wittig reagent, where the ethyl group is fully substituted with deuterium atoms. This compound is critical for introducing deuterium labels into organic molecules, enabling advanced research in reaction mechanism elucidation, metabolic studies, and the synthesis of isotopically labeled standards. It is primarily sought by researchers and process chemists in the pharmaceutical, agrochemical, and analytical chemistry sectors for applications in drug discovery and development.

Application

• Deuterium-Labeled Compound Synthesis: As a key Wittig reagent for the preparation of olefins and other complex molecules with site-specific deuterium incorporation.
• Pharmaceutical Research: Synthesis of deuterated drug candidates and internal standards for use in pharmacokinetic, metabolic stability, and mass spectrometry (MS) analysis.
• Mechanistic Studies: Employed as a tracer in reaction kinetic studies and to investigate chemical and biochemical pathways using techniques like NMR and MS.
• Agrochemical Development: Creation of isotopically labeled pesticides or herbicides for environmental fate and metabolism studies.
• Material Science: Potential use in the synthesis of deuterated polymers or organic electronic materials for specialized property analysis.
• Analytical Reference Standards: Production of high-purity, certified reference materials (CRMs) for quantitative analysis in regulated laboratories.

Basic Information

Product Name	(Ethyl-D5)Triphenylphosphonium Bromide
CAS No.	875477-12-6
Molecular Formula	C20H15D5BrP
Molecular Weight	374.27 g/mol
Synonyms	Deuterated Ethyltriphenylphosphonium Bromide; (Pentadeuteroethyl)triphenylphosphonium Bromide; Ethyl-d5 Triphenylphosphonium Bromide; (C2D5)PPh3Br; Wittig Reagent-d5; Triphenyl(pentadeuteroethyl)phosphonium Bromide; 875477-12-6
EINECS	Contact for details

Quality Control

Every batch of (Ethyl-D5)Triphenylphosphonium Bromide is manufactured and tested under strict quality management protocols. We ensure high chemical purity and isotopic enrichment, with comprehensive analysis including NMR (¹H, ¹³C, ³¹P) and Mass Spectrometry to confirm structure and deuterium content. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and relevant physical data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Content (MS/NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.