Description

6-Fluoro-5-Trifluoromethyl-1H-Indole is a high-value, multi-fluorinated indole derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart desirable properties such as enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine motifs contribute to efficacy and environmental profile.
• Material Science Research: Employed in the synthesis of specialized fluorinated polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a core structure for developing fluorescent tags and molecular probes for diagnostic and research applications.
• Catalyst & Ligand Development: Utilized as a precursor for creating novel ligands in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	6-Fluoro-5-Trifluoromethyl-1H-Indole
CAS No.	875306-79-9
Molecular Formula	C9H5F4N
Molecular Weight	203.14 g/mol
Synonyms	5-(Trifluoromethyl)-6-fluoro-1H-indole; 6-Fluoro-5-(trifluoromethyl)indole; 1H-Indole, 6-fluoro-5-(trifluoromethyl)-; 6-Fluoro-5-trifluoromethylindole; 875306-79-9
EINECS	Contact for details

Quality Control

Our 6-Fluoro-5-Trifluoromethyl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.