Description

5-(Trifluoromethyl)-1H-Indole-7-Carboxylic Acid is a high-value, multi-functional indole derivative characterized by its trifluoromethyl group and carboxylic acid functionality. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-inflammatory research.
• Agrochemical Development: Used in creating advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, amide bond formation, and as a precursor for more complex heterocyclic systems.
• Material Science Research: Investigated for the development of organic semiconductors, liquid crystals, and specialty polymers due to its unique electronic properties.
• Fluorine Chemistry Studies: Serves as a model compound for studying the influence of the trifluoromethyl group on indole chemistry and reactivity.

Basic Information

Product Name	5-(Trifluoromethyl)-1H-Indole-7-Carboxylic Acid
CAS No.	875306-19-7
Molecular Formula	C10H6F3NO2
Molecular Weight	229.16 g/mol
Synonyms	7-Carboxy-5-(trifluoromethyl)indole; 1H-Indole-7-carboxylic acid, 5-(trifluoromethyl)-; 5-Trifluoromethyl-1H-indole-7-carboxylic acid; 5-(Trifluoromethyl)indole-7-carboxylic acid; 875306-19-7; 5-CF3-1H-Indole-7-COOH
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1H-Indole-7-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.