Description

2-Methyl-2,3-Dihydro-1H-Indole-5-Sulfonic Acid Amide is a specialized heterocyclic sulfonamide building block of significant interest in advanced organic synthesis. Its core indoline scaffold fused with a sulfonamide functional group makes it a valuable intermediate for the development of novel pharmacologically active compounds. This high-purity chemical is primarily targeted at research and development teams within the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Research: Serves as a building block in the synthesis of novel herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Dye and Pigment Chemistry: Used in the synthesis of specialized indoline-based dyes and functional colorants due to its electron-donating and sulfonamide-substituted aromatic system.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the development of advanced polymers, coatings, or organic electronic materials.
• Chemical Biology Probe Development: Employed in creating molecular probes and inhibitors for studying enzyme function and biological pathways in academic and industrial research settings.

Basic Information

Product Name	2-Methyl-2,3-Dihydro-1H-Indole-5-Sulfonic Acid Amide
CAS No.	875163-03-4
Molecular Formula	C9H12N2O2S
Molecular Weight	212.27 g/mol
Synonyms	5-Sulfamoyl-2-methyl-2,3-dihydro-1H-indole; 2-Methyl-2,3-dihydroindole-5-sulfonamide; 2-Methylindoline-5-sulfonamide; 1H-Indole-5-sulfonamide, 2,3-dihydro-2-methyl-; 2-Methyl-2,3-dihydro-1H-indol-5-ylsulfonamide; 5-Sulfonamido-2-methylindoline; 2-Methyl-1,2,3,4-tetrahydro-5-indolesulfonamide
EINECS	Contact for details

Quality Control

Our 2-Methyl-2,3-Dihydro-1H-Indole-5-Sulfonic Acid Amide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.