Description

5-(1H-Indol-3-Yl)-4-Methyl-4H-1,2,4-Triazole-3-Thiol is a high-purity heterocyclic organic compound that serves as a critical advanced intermediate in pharmaceutical and agrochemical research. Its unique molecular architecture, featuring fused indole and triazole-thiol moieties, makes it a versatile building block for the synthesis of novel bioactive molecules. This compound is primarily utilized by R&D chemists and process development scientists in the life sciences sector for creating potential drug candidates and specialized chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting various therapeutic areas, including oncology and neurology.
• Agrochemical Research: Building block for developing new-generation pesticides and herbicides with specific modes of action.
• Chemical Biology Probe: Used in medicinal chemistry to study enzyme inhibition and receptor-ligand interactions due to its heterocyclic structure.
• Material Science Research: Potential monomer or additive in the development of specialty polymers and functional materials.
• Academic & Institutional R&D: Serves as a reference standard and starting material in university and government laboratory research projects.

Basic Information

Product Name	5-(1H-Indol-3-Yl)-4-Methyl-4H-1,2,4-Triazole-3-Thiol
CAS No.	874782-55-5
Molecular Formula	C11H10N4S
Molecular Weight	230.29 g/mol
Synonyms	4-Methyl-5-(1H-indol-3-yl)-4H-1,2,4-triazole-3-thiol; 3-Thiol-4-methyl-5-(3-indolyl)-1,2,4-triazole; 5-(3-Indolyl)-4-methyl-1,2,4-triazole-3-thiol; 4-Methyl-5-(indol-3-yl)-1,2,4-triazole-3-thiol; 1,2,4-Triazole-3-thiol, 4-methyl-5-(1H-indol-3-yl)-; 874782-55-5; 5-(1H-Indol-3-yl)-4-methyl-4H-1,2,4-triazole-3-thiol
EINECS	Contact for details

Quality Control

Our 5-(1H-Indol-3-Yl)-4-Methyl-4H-1,2,4-Triazole-3-Thiol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or when opening the primary container. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.