Description

1-(1,3-Thiazol-2-Yl)Piperidine-4-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical researchers and fine chemical manufacturers need it for its unique structural motif, which is valuable in medicinal chemistry programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its privileged piperidine-thiazole scaffold.
• Agrochemical Synthesis: Serves as a precursor in the development of new crop protection agents and pesticides, leveraging its heterocyclic core.
• Ligand and Catalyst Development: Employed in the design of novel ligands for metal catalysis and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial quantities for research.

Basic Information

Product Name	1-(1,3-Thiazol-2-Yl)Piperidine-4-Carboxylic Acid
CAS No.	874623-60-6
Molecular Formula	C9H12N2O2S
Molecular Weight	212.27 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-(2-thiazolyl)-; 1-(Thiazol-2-yl)piperidine-4-carboxylic acid; 1-(1,3-Thiazol-2-yl)piperidine-4-carboxylic acid; 2-(4-Carboxypiperidin-1-yl)thiazole; UNII-9F4K8Q4Q5F; 9F4K8Q4Q5F; Thiazol-2-yl-piperidine-4-carboxylic acid; Piperidine-4-carboxylic acid, 1-(1,3-thiazol-2-yl)-
EINECS	Contact for details

Quality Control

Our 1-(1,3-Thiazol-2-Yl)Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.