Description

5-(Morpholin-4-Ylsulfonyl)Indoline is a specialized sulfonamide-based heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a morpholine sulfonyl group with an indoline scaffold, making it a versatile intermediate for constructing complex pharmacophores. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its sulfonamide functionality for biological activity.
• Chemical Biology Probe: Serves as a core structure for designing molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers or organic electronic materials due to its fused ring system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring this precise scaffold.

Basic Information

Product Name	5-(Morpholin-4-Ylsulfonyl)Indoline
CAS No.	874594-02-2
Molecular Formula	C12H16N2O3S
Molecular Weight	268.33 g/mol
Synonyms	5-(Morpholinosulfonyl)indoline; 5-(4-Morpholinylsulfonyl)-2,3-dihydro-1H-indole; 1H-Indole, 2,3-dihydro-5-[(4-morpholinyl)sulfonyl]-; Indoline, 5-(morpholin-4-ylsulfonyl)-; 874594-02-2; 5-Morpholinosulfonylindoline; 5-(N-Morpholinosulfonyl)indoline
EINECS	Contact for details

Quality Control

Every batch of 5-(Morpholin-4-Ylsulfonyl)Indoline is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (HPLC), identity (NMR, IR), and impurity profile. Our quality commitment supports compliance in cGMP and ISO 9001 environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.