Description

B-[4-[[(2-Thienylmethyl)Amino]Carbonyl]Phenyl]Boronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its molecular architecture, featuring both a boronic acid group and a thienylmethyl amide moiety, makes it a versatile intermediate for constructing complex molecules via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require high-purity, functionalized intermediates for drug discovery and specialty polymer synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for Suzuki-Miyaura cross-coupling reactions to form biaryl structures.
• Organic Light-Emitting Diode (OLED) Materials: Used in the development of electron-transport or emissive layer materials for display and lighting technologies.
• Ligand for Catalysis: Can be utilized to create novel ligands for transition metal catalysts used in asymmetric synthesis.
• Polymer & Material Science: Serves as a monomer or functionalization agent in the production of specialty polymers, such as conductive or self-healing materials.
• Chemical Biology & Probe Development: Employed in the design of molecular probes and sensors that leverage boronic acid-diol interactions for detecting sugars or other analytes.
• Agrochemical Research: Acts as an intermediate in the synthesis of novel crop protection agents with complex aromatic frameworks.

Basic Information

Product Name	B-[4-[[(2-Thienylmethyl)Amino]Carbonyl]Phenyl]Boronic Acid
CAS No.	874460-04-5
Molecular Formula	C13H14BNO3S
Molecular Weight	275.13 g/mol
Synonyms	[4-[[(2-Thienylmethyl)carbamoyl]phenyl]boronic acid; 4-[(Thiophen-2-ylmethyl)carbamoyl]phenylboronic acid; (4-{[(Thiophen-2-ylmethyl)amino]carbonyl}phenyl)boronic acid; Boron, [4-[[[(2-thienylmethyl)amino]carbonyl]phenyl]-, hydroxy complex; 4-Carbamoylphenylboronic acid thienylmethyl derivative; p-Boronobenzamide, N-(2-thienylmethyl)-; 874460-04-5; Boronic acid, B-[4-[[(2-thienylmethyl)amino]carbonyl]phenyl]-
EINECS	Contact for details

Quality Control

Our B-[4-[[(2-Thienylmethyl)Amino]Carbonyl]Phenyl]Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.