Description

Boronic Acid, [2-(1-Piperidinylcarbonyl)Phenyl]- is a specialized organoboron compound featuring a phenylboronic acid core linked to a piperidinecarboxamide moiety. This structure is highly valuable as a key synthetic intermediate and ligand in modern organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules via Suzuki-Miyaura cross-coupling and other catalytic transformations.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling: Acts as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, essential for creating biaryl structures in drug discovery.
• Ligand in Catalysis: The amide and piperidine functionalities can be exploited in the design of novel ligands for transition metal catalysis.
• Agrochemical Research: Used in the development of new crop protection agents and herbicides requiring specific boronic acid intermediates.
• Material Science: Potential precursor for the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Can be utilized in the development of sensors or probes targeting biomolecules with diol groups.

Basic Information

Product Name	Boronic Acid, [2-(1-Piperidinylcarbonyl)Phenyl]-
CAS No.	874459-82-2
Molecular Formula	C13H18BNO3
Molecular Weight	247.10 g/mol
Synonyms	(2-(Piperidine-1-carbonyl)phenyl)boronic acid; 2-(1-Piperidinecarbonyl)benzeneboronic acid; 2-(Piperidine-1-carbonyl)phenylboronic acid; [2-(Piperidine-1-carbonyl)phenyl]boronic acid; 2-Carbamoylphenylboronic acid piperidine derivative; B-[2-(1-Piperidinylcarbonyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our Boronic Acid, [2-(1-Piperidinylcarbonyl)Phenyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.