Description

4-(4-Chlorophenylcarbamoyl)Phenylboronic Acid is a high-purity, functionalized boronic acid derivative designed for advanced chemical synthesis. This compound is a critical building block in modern pharmaceutical and agrochemical research, enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the life sciences and fine chemical industries for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific chlorophenyl and carbamoyl functionalities.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers, such as boron-containing polyamides or specialty resins.
• Suzuki-Miyaura Cross-Coupling: An essential boronic acid reagent for palladium-catalyzed coupling reactions to construct complex, conjugated organic molecules.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors that target specific biological pathways.
• Liquid Crystal & OLED Materials: A building block for creating advanced organic electronic materials with tailored electronic properties.

Basic Information

Product Name	4-(4-Chlorophenylcarbamoyl)Phenylboronic Acid
CAS No.	874288-02-5
Molecular Formula	C13H11BClNO3
Molecular Weight	275.49 g/mol
Synonyms	[4-(4-Chlorophenylcarbamoyl)phenyl]boronic acid; 4-Carbamoylphenylboronic acid, 4'-chloro- derivative; B-[4-[[(4-Chlorophenyl)amino]carbonyl]phenyl]boronic acid; 4-(4-Chlorophenylaminocarbonyl)benzeneboronic acid; 4-Chlorophenyl 4-boronobenzamide; (4-((4-Chlorophenyl)carbamoyl)phenyl)boronic acid; 4-Boronobenzoic acid (4-chlorophenyl)amide
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Chlorophenylcarbamoyl)Phenylboronic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for research and commercial synthesis. Our quality control protocols include identity confirmation, purity assay, and impurity profiling. A detailed Certificate of Analysis (COA) documenting purity (typically ≥95% by HPLC), appearance, and specific tests is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.