Description

Cholesteryl-Teg Cep CAS NO 873435-29-1 is a high-purity, synthetic cholesterol derivative, specifically engineered as a key intermediate for advanced pharmaceutical and biomedical research. This compound is critical for the development and formulation of novel drug delivery systems, including liposomes and lipid nanoparticles, due to its ability to modulate membrane stability and functionality. It is an essential material for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors seeking to innovate in targeted therapies and diagnostic agents.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A critical structural component for enhancing the stability, circulation time, and targeting efficiency of encapsulated therapeutic agents.
• Drug Delivery System Development: Used in the research and production of advanced carriers for mRNA vaccines, siRNA, chemotherapeutics, and other bioactive molecules.
• Biomimetic Membrane Research: Serves as a model compound in biophysical studies to understand cell membrane properties, cholesterol trafficking, and protein-lipid interactions.
• Diagnostic Agent Synthesis: Acts as a precursor or conjugate in the creation of contrast agents and probes for imaging technologies.
• Bioconjugation and Linker Chemistry: The functionalized "Teg" (triethylene glycol) spacer enables further chemical modification and attachment to targeting ligands or other molecules.
• Cosmetic and Dermatological Formulations: Employed in high-end skincare products for its membrane-stabilizing and delivery-enhancing properties.

Basic Information

Product Name	Cholesteryl-Teg Cep
CAS No.	873435-29-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cholesteryl-Triethylene Glycol Cep; Cholesterol-PEG3-Cep; 3β-[(2-{2-[2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}ethoxy)-5-cholestene; Cholesterol-(EO)3-Maleimide; N-(3-Cholest-5-en-3β-yloxy-2-{2-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]ethoxy}ethyl)maleimide; Maleimide-PEG3-Cholesterol
EINECS	Contact for details

Quality Control

Our Cholesteryl-Teg Cep is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.